Papers (Students and Postdocs in Bold)

  1. Steimle, L., Ahluwalia, V., Kamdar, C., Denton, B.T.,  “Decomposition Methods for Solving Multi-model Markov Decision Processes.” (under review: available at Optimization Online:
  2. Barnett, C., Davenport, M.S., Montgomery, J.S., Kunju, L.P., Denton, B.T., Piert, M., 18F-choline PET/mpMRI for Detection of Significant Prostate Cancer: Part 2. Cost-Effectiveness Analysis,  Journal of Nuclear Medicine (in press) 2019
  3.  Denton, B. T. (2018). “Optimization of Sequential Decision Making for Chronic Diseases: From Data to Decisions.” In Recent Advances in Optimization and Modeling of Contemporary Problems (pp. 316-348). INFORMS.
  4. Harvey, M. J., Denton, B. T., Prosser, L. A., & Hutton, D. W. (2018). “Determining the optimal strategy for the live-attenuated herpes zoster vaccine in adults. ” Vaccine36(41), 6237-6247.
  5. Barnett, C. L., Davenport, M. S., Montgomery, J. S., Wei, J. T., Montie, J. E., & Denton, B. T. (2018). “Cost‐effectiveness of magnetic resonance imaging and targeted fusion biopsy for early detection of prostate cancer.” BJU international.
  6. Steimle, L, Kauffman, D., Denton, B.T., “Multi-model Markov Decision Processes: A New Method for Mitigating Parameter Ambiguity,” Working Paper (under review, available at Optimization Online:, 2018
  7. Mason, J.E., Denton, B.T., Shah, N.D., Smith, S.A., “Using Electronic Health Records to Monitor and Improve Adherence to Medication,” IISE Transactions on Healthcare Systems Engineering, 7(4); 194-214, 2018
  8. Merdan, S., Barnett, C., Denton, B.T., Montie, J., Miller, D.,  “Data Analytics for Optimal Detection of Metastatic Prostate Cancer,” Working Paper (under review), 2017
  9. Barnett, C., Auffenberg, G., Cheng, Z., Yang, F., Wang, J., Wei, J., Miller, D., Montie, Mamawala, M., Denton, B.T., “Optimizing Active Surveillance Strategies to Balance Competing Goals of Early Detection of Prostate Cancer , ” Cancer; 124(4); 698-755, 2017.
  10. Berg, B., Denton, B.T., “Fast Approximations for Online Scheduling of Outpatient Procedure Centers,” INFORMS Journal on Computing; 29(4); 631-644, 2017
  11. Zhang, Y., Mason, J.E., Wu, H., Wilson, J., Denton, B.T., “Conducting Probabilistic Sensitivity Analysis for Markov Decision Processes,” Healthcare Management Science (in press), 2017.
  12. Barnett, C.L., Tomlins, S.A., Underwood, D.J., Morgan, T.M., Montie, J.E., Wei, J.T., Denton, B.T., “Two-Stage Biomarker Protocols for Improving the Early Detection of Prostate Cancer,” Medical Decision Making; 37(7), 815-826, 2017.
  13. Basu, S., Sussman,J.B., Rigdon, J., Steimle L., Denton, B.T., Hayward, R.A., “ Improved Targeting of  Intensive Blood Pressure Treatment: Derivation and Validation of Risk Scores for Benefit and Harm,” PLOS Medicine; 14(10), e1002410, 2017
  14. Barnett, C.L., Davenport, M., Montgomery, J., Wei, J., Montie, J., Denton, B.T., “Cost‐effectiveness of magnetic resonance imaging and targeted fusion biopsy for early detection of prostate cancer,” BJU International, 2017
  15. Bam, M., Denton, B.T., Van Oyen, M., “Surgery Scheduling with Recovery Resources,” IISE Transactions; 49(1), 1-14, 2017
  16. Zheng, Z., Denton, B.T., Xie, X., “Appointment Scheduling and the Effects of Customer Congestion on Service,” Working Paper, 2016
  17. Zhang, Y., Denton, B.T., “Robust Markov Decision Processes for Medical Treatment Decisions,” Working Paper (under review, available at Optimization Online, 2016
  18. Zheng, Z., Denton, B.T., Xie, X., “Branch-and-Price for Stochastic Bin Packing,” Working Paper (under review, available at Optimization Online:, 2016
  19. Steimle, L., Denton, B.T., “Screening and Treatment of Chronic Diseases,” Markov Decision Processes in Practice, Eds: Richard Boucherie and Nico M. van Dijk, Springer, New York, 2016
  20. Hurley, P., Dhir, A., Gao, Y., Drabik, B., Lim, K., Curry, J., Womble, P.R., Linsell, S.M., Brachulis, A., Sexton, D.W., Ghani, K.R., Denton, B.T., Miller, D.c., Montie, J.E. “A State-wide Intervention Improves Appropriate Imaging in Localized Prostate Cancer,” Urology, 197(50); 1222-1228, 2016
  21. Castaing, J., Cohn, A., Denton, B.T., “A Stochastic Programming Approach to Reduce Patient Wait Times and Overtime in an Outpatient Infusion Center,” IIE Transactions on Healthcare Systems Engineering, 6(3), 111-125, 2016
  22. Albey, E., Gose, A.H., Nourouzi, A., Denton, B.T., Kempf, K.G., Uzsoy, R., “A Comparison of Multi-Stage Stochastic Programming and Chance Constrained Programming for Production Planning with Forecast Evolution,” Working Paper (under review), 2015
  23. Underwood, D., Zhang, J., Nielsen, M.E., Wilson, J.R., Denton, B.T., “The Influence of Heterogeneity on the Harms and Benefits of Prostate Cancer Screening,” Working Paper, 2015
  24. Liu, J., Womble, P.R., Merdan, S., Miller, D.C., Montie, J.E., Denton, B.T., “Factors Influencing Selection of Active Surveillance for Localized Prostate Cancer,” Urology, 86, 901-905, 2015.
  25. Merdan, S., Tomlins, S.A., Barnett, C.L., Underwood, D.J., Morgan, T.M., Montie, J.E., Wei, J.T., Denton, B.T., “Assessment of Long Term Outcomes Associated with Urinary Prostate Cancer Antigen 3 and TMPRSS2:ERG Gene Fusion at Repeat Biopsy,” Cancer (in press), 2015.
  26. Gul, S., Denton, B.T., Fowler, J., “A Multi-Stage Stochastic Integer Programming Model for Surgery Planning,” INFORMS Journal on Computing (in press), 2015.
  27. Bam, M., Denton, B.T., Van Oyen, M., Cowen, M., “Surgery Scheduling with Recovery Resources,” Working Paper, 2015.
  28. Erdogan, S.A., Ghose, A., Denton, B.T., “On-line Appointment Sequencing and Scheduling,” IIE Transactions, 47, 1267-1286, 2015.
  29. McCoy, R.G., Zhang, Y., Denton, B.T., Mason, J., Montori, V.M., Smith, S.A., Shah, N., “Trends in Treatment Intensification of Type 2 Diabetes,” American Journal of Managed Care, 2015.
  30. Price, S., Golden, B., Wasil, E., Denton, B.T., “Operations Research Models and Methods in the Screening, Detection, and Treatment of Prostate Cancer: A Categorized, Annotated Bibliography,” Operations Research for Health (in press), 2015
  31. Milne, R.J., White, T., Denton, B.T., “The Art and Science of Practice: How Analytics Practitioners Can Learn from Published Patents and Protect Their Work,” Interfaces, 45(3), 271-277, 2015
  32. Gose, A., Denton, B.T., “Sequential Bounding Methods for Two Stage Stochastic Programs,” INFORMS Journal on Computing (in press) (available at, 2014
  33. Deng, Y., Shen, S., Denton, B.T., “Chance-Constrained Surgery Planning Under Uncertain or Ambiguous Surgery Durations,” Working Paper (available at Social Science Research Network:, 2014
  34. Merdan, S., Womble, P.R., Miller, D.C., Barnett, C, Ye, Z., Linsell, S.M., Montie, J.E., Denton, B.T., “Towards Better Use of Bone Scans Among Men with Early State Prostate Cancer,” Urology, 84: 793-798, 2014
  35. Risko, R., Merdan, S. Womble, P.R., Montie, J., Barnett, C., Ye, Z., Linsell, S., Miller, D., Denton, B.T., “Clinical Predictors and Recommendations for Staging CT Scan Among Men with Prostate Cancer,” Urology, 84, 1329-1334 ,2014.
  36. Zhang, Y., McCoy, R.G., Mason, J., Smith, S.A., Shah, N., Denton, B.T., “Comparative Analysis of Treatment Regimens for Glycemic Control in Diabetes Patients,” Diabetes Care 37:5 1338-1345, 2014.
  37. Bjorn Berg, Denton, B.T., Ayca Erdogan, Todd Huschka, Thomas Rohleder, “Optimal Overbooking Strategies for Outpatient Procedure Centers,” Computers & Operations Research, 50, 24-37, 2014
  38. Wang, C.T., Milne, R.J., Fordyce, K., Denton, B.T., “Incorporating Contractual Arrangements in Production Planning,” Computers & Operations Research, 53, 353-363, 2015
  39. Mason, J., Denton, B.T., Shah, N., Smith, S., “Optimizing the Simultaneous Management of Cholesterol and Blood Pressure Treatment Guidelines for Patients with Type 2 Diabetes,” European Journal of Operational Research, 233, 727-738, 2013.
  40. Berg, B. , Murr, M. , Chermak, D., Woodall, J. , Pignone, M., Sandler, R., Denton, B.T., “Estimating the Cost of No-shows and Evaluating the Effects of Mitigation Strategies,” Medical Decision Making, 33, 976-985, 2012.
  41. Yarmand, H., Ivy, J., Denton, B.T., Loyd, A., “Optimal Two-Phase Vaccine Allocation to Geographically Different Regions under Uncertainty,” European Journal of Operational Research 233(1), 208-219, 2014.
  42. Zhang, Y. , Nielsen, M., Denton, B.T., “Comparison of Surveillance Strategies for Low Risk Bladder Cancer Patients,” Medical Decision Making 33, 198-214, 2013.
  43. Erdogan, S.A., Denton, B.T., “Dynamic Appointment Scheduling with Uncertain Demand,” INFORMS Journal on Computing 25(1), 116-132, 2013.
  44. Woodall, J., Gosselin, T., Boswell, A., Murr, M., Denton, B.T., “A Simulation Optimization Approach to Improve Patient Access to Duke Medicine’s Cancer Center,” Interfaces 43(5), 449-461, 2013. (Finalist for 2012 INFORMS Daniel H. Wagner Prize).
  45. Zhang, J., Denton, B.T., Balasubramanian, H., Inman, B., Shah, N., “Optimization of Prostate Biopsy Referral Decisions,” Manufacturing & Service Operations Management , 14(4), 529-547, 2012.
  46. Underwood, D., Zhang, J., Denton, B.T., Shah, N., Inman, B., “Simulation Optimization of PSA Threshold Based Prostate Cancer Screening Policies,” Health Care Management Science, 15(4), 293-309, 2012.
  47. Zhang, J., Denton, B.T., Balasubramanian, H., Inman, B., Shah, N., “Optimization of PSA Screening Policies: A Comparison of the Patient and Societal Perspectives,” Medical Decision Making, 32(2), 337-349, 2012.
  48. Inman, B., Zhang, J., Shah, N., Denton, B.T., “An Evaluation of the Dynamic Changes in PSA Occurring in a Population-Based Cohort of Men Over Time,” British Journal of Urology International, 110(3), 375-381, 2012.
  49. Mason, J., Denton, B.T.,“A Comparison of Decision Maker Perspectives on the Optimal Time to Initiate Cholesterol Treatment,” IBM Journal on Research and Development, 56(5), 1-12, 2012.
  50. Mason, J.E., England, D., Denton, B.T., Smith, S., Kurt, M., Shah, N., “Optimizing Statin Treatment Decisions in the Presence of Uncertain Future Adherence,” Medical Decision Making 32(1), 154-166, 2012.
  51. Berg, B, Denton, B.T., “Appointment Planning and Scheduling in Outpatient Procedure Centers,” in Springer Handbook of Healthcare System Scheduling, Springer, 2012.
  52. Degbotse, A., Denton, B., Fordyce, K., Milne, R.J., Orzell, R., and Wang, C., “IBM Blends Heuristics and Optimization to Plan its Semiconductor Supply Chain,” Interfaces, 43(2), 130-141, 2013.
  53. Denton, B.T., Alagoz, O., Holder, A., Lee, E, “Open Challenges in Medical Decision Making,” IIE Transactions on Healthcare Engineering 1(3), 161-167, 2011.
  54. Batun, S., Denton, B.T., Huschka, T.R., Schaefer, A.J., “The Benefit of Pooling Operating Rooms Under Uncertainty,” INFORMS Journal on Computing, 23(2), 220-237, 2011
  55. Gul, S., Denton, B.T., Huschka, T., Fowler, J.R., “Bi-criteria Evaluation of an Out Patient Surgery Clinic via Simulation,” Production and Operations Management, 20(3), 406-417, 2011
  56. Kurt, M., Denton, B.T., Schaefer, A., Shah, N., Smith, S., “The Structure of Optimal Statin Initiation Policies for Patients with Type 2 Diabetes”, IIE Transactions on Healthcare 1, 49-65, 2011 (Finalist INFORMS 2009 “Doing Good with Good OR – Student Paper Competition”, Winner of the 2010 INFORMS Service Section Best Paper Award).
  57. Shah, N.D., Mason, J.E., Kurt, M., Denton, B.T., Schaefer, A.J., Montori, V.M., Smith, S.A., “Comparative Effectiveness of Guidelines for the Management of Hyperlipidemia and Hypertension for Type 2 Diabetes Patients,” PLoS ONE, 6(1): e16170, 2011
  58. Balasubramanian, H., Banerjee, R., Naessens, J.M., Denton, B.T., Wood, D.L., “Improving Clinical Access and Continuity through Physician Panel Redesign,” Journal of General Internal Medicine, 25(1), 1109-1115, 2010
  59. Balasubramanian, H., Denton, B.T., “Managing Physician Panels in Primary Care,” Handbook of Health Care Delivery Systems, edited by Yih, Y., CRC Press, 2009.
  60. Denton, B.T., Verter, C., “OR in Healthcare“, OR/MS Today, 37(5), 2010
  61. Woodall, J., Berg, B., Sandler, R., Walker, M., Denton, B.T., “The Operational Performance Impact of Propofol on Patient Throughput in an Outpatient Endoscopy Suite,” Working Paper, 2010
  62. Denton, B.T., Miller, A., Balasubramanian, H., Huschka, T., “Optimal Allocation of Surgery Blocks to Operating Rooms Under Uncertainty,” Operations Research 58(4), 802-816, 2010
  63. Zhang, J., Mason, J.E., Denton, B.T., Pierskalla, W.P., “Applications of Operations Research to the Prevention, Detection, and Treatment of Disease,” Wiley Encyclopedia of Operations Research and Management Science, 2010
  64. Rohleder, T., Huschka, T., Denton, B.T., “Using Simulation to Design and Improve an Outpatient Procedure Center,” Management Engineering for Effective Healthcare Delivery: Principles and Applications, IGI Global Publishers, 2010.
  65. Erdogan, S.A., Denton, B.T., “Surgery Planning and Scheduling: A Literature Review,” Wiley Encyclopedia of Operations Research and Management Science, 2010
  66. Berg, B., Denton, B.T., Nelson, H., Balasubramanian, B., Rahman, A., Bailey, A., Lindor, K., “A Computer Simulation Model to Evaluate Operational Performance of a Colonoscopy Suite,” Medical Decision Making, 30, 380-387, 2009
  67. DeLergio, S., Denton, B.T., Cabanela, R.L., Anderson, S.S., Bruggeman, S.K., Ward, S.L., Groves, N., Osborn, J. “Forecasting Outpatient Visits to Improve Patient Access at a Large Medical Center,” Journal of Production and Inventory Management, 45(2), 35-58, 2009
  68. Fordyce, K., Wang, C., Chang, C., Degbotse, A., Denton, B.T., Lyon, P., Milne, R.J., Orzell, R., Rice, R., Waite, J., “The Ongoing Challenge – Creating an Enterprise-Wide Detailed Supply Chain Plan for Semiconductor and Package Operations,” Handbook of Production Planned, edited by Kempf, K., Keskinocak, P., Uzsoy, R., Kluwer Academic Publishers, 2009.
  69. Denton, B.T., Kurt, M., Shah, N.D., Bryant, S.C., Smith, S.A., “A Markov Decision Process for Optimizing the Start Time of Statin Therapy for Patients with Diabetes,” Medical Decision Making, 29(3), 351-367, 2008
  70. Gupta D, Denton, B.T. “Health Care Appointment Systems: Challenges and Opportunities,” IIE Transactions, 40, 800-819, 2008
  71. Huschka, T., Denton, B.T., Narr, B., Thompson, A., “Using Simulation in the Implementation of an Outpatient Procedure Center,” Winter Simulation Conference Proceedings, Miami, FL, 2008
  72. Iser, J., Denton, B.T., King, R. “Heuristics for Balancing Operating Room and Post-Anesthesia Resources Under Uncertainty,” Winter Simulation Conference Proceedings, Miami, FL, 2008
  73. Huschka, T., Denton, B.T., Gul, S., Fowler, J.R., “Bi-criteria Evaluation of an Out Patient Surgery Clinic via Simulation,” Winter Simulation Conference Proceedings, Washington, D.C., 2007
  74. Balasubramanian, H., Banerjee, R., Gregg, M., Denton, B., “Improving Primary Care Access Using Simulation Optimization,” Winter Simulation Conference Proceedings, Washington, D.C., 2007
  75. Denton, B.T., Viapiano, J., Vogl, A., “Optimization of Surgery Sequencing and Start Time Scheduling Decisions,” Health Care Management Science, 10(1), 13-24, 2007
  76. Denton, B.T., Rahman, A, Nelson, H., Bailey, A, “Simulation of a Multiple Operating Room Surgical Suite,” Winter Simulation Conference Proceedings, Monterey, CA, 2006
  77. Denton, B.T., Forrest, J., Milne, J., 2006, “IBM Solves a Mixed-Integer Program to Optimize Its Semiconductor Supply Chain,” Interfaces, 36, 386-399 (2005 INFORMS Daniel H. Wagner Prize Winner)
  78. Denton, B.T., and Gupta D., 2004, “Strategic Inventory Deployment in the Steel Industry,” IIE Transactions, 36, 1083-1097. (Feature article in IE Magazine, November 2004)
  79. Denton, B.T. and Gupta D., 2003, “A Sequential Bounding Approach for Optimal Appointment Scheduling,” IIE Transactions, 35, 1003-1016 (2005 Outstanding IIE Publication Award 2005, and feature article in IE Magazine, November 2003)
  80. Denton, B.T., Gupta D., and Jawahir K., 2003, “Managing Increasing Product Variety at Integrated Steel Mills,” Interfaces, 33, 41-53.
  81. Denton, B.T. and Gupta D., “Optimization of Appointment Based Service Systems,” MSOM Conference Proceedings, Ann Arbor, 2000


Publication Links

Google Citations

National Center for Biotechnology Information (NCBI) Bibliography

Research Gate


  1. Denton, B.T. (Ed.), “Handbook of Healthcare Operations Management: Methods and Applications,” International Series in Operations Research and Management Science, Volume 84, Springer, New York.

Undergraduate Research Projects

  1. Chen, Z., Yang, F., Wang, J. (UM-SURE Project), “Hidden Markov Models for Estimation of Prostate Cancer Progression in Men Receiving Active Surveillance,” (Summer, 2016)
  2.  Wang, J., “Statistical Modeling of Longitudinal Data to Simulate Cardiovascular Risk Progression in Patients Over Time,” (Fall 2015, Spring 2016, Fall 2016)
  3. Correa, M., University of Michigan (UM SROP-Project), “Statistical Validation of Predictive Models for Cancer Imaging”, 2014
  4. Jianyu, L., University of Michigan (UM – SURE), “Statistical Models for Evaluating Decisions to Pursue Active Surveillance for Low Grade Prostate Cancer”, 2014
  5. Risko, R., University of Michigan, “Predictive Models for CT Imaging in Prostate Cancer”, 2013-2014
  6. Pixton, D., Berg, B., Hopper, T., Denton, B.T., NCSU, 2012, “A Simulation Model for Operational Improvements of University of North Carolina Cancer Hospital Infusion Clinic”
  7. Chermak, D., NCSU, 2010, “Analysis of Scheduling Heuristics in the Presence of No-Shows for an Endoscopy Practice at UNC Hospital”
  8. Chang, C., Weikert, E., NCSU, 2010, “Staffing of In Room Providers For Surgery at Mayo Clinic”
  9. Johnson, J., Wood, J., Berg, B., Denton, B.T., NCSU, 2009, “Analysis of Endoscopy Suites at University of North Carolina Hospitals”
  10. Plack, S., Moomaw, L., Carr, S., Denton, B.T., NCSU, 2009, “Optimal Location of Nerve Agent Chem-Packs in North Carolina” (Fall 2008 – Spring 2009 (Poster Presentation., at North Carolina Public Health Association Annual Conference, Asheville, NC, September 2009)
  11. Carter, A., Squires, R., NCSU, 2009, “A Simulation Model to Evaluate the Effect of New System Interventions for an Urgent Care Clinic,” (Poster Presentation at Society for General Internal Medicine Annual Meeting, Orlando, FL, May 2009)
  12. Diering, M., Goodell, ,K., Johnson, D., Denton, B.T., NCSU, 2008, “A Simulation Model for Analysis of Patient Flow Through UNC Family Medicine Clinic”
  13. Adams, Z., Moore, K., Wampler, A., Erdogan, A., Denton, B.T., NCSU, 2008, “Surgery Scheduling Decision Support System,” (1st Place, IIE Society for Health Systems Student Paper Award, Chicago, IL, 2009) (Spring 2008)
  14. Wilson, Z., Denton, B.T., NCSU, 2008, “Optimization of Patient Access to Health Services”
  15. Dunn, B., Wilson, L., Denton, B.T., NCSU, 2007, “NCSU Robotic Surgery Evaluation Project”